Cannabidiol (CBD) derived from the cannabis plant possesses many health benefits making it useful in the treatment of diseases. People are using products made from it in the treatment of common ailments like headaches, muscle and joint pains, inflammation, bruises, minor wounds etc. Apart from this it’s oral consumption helps to stimulate appetite, as well as in preventing nausea and vomiting. The purpose of this primer is to get a better understanding of CBD for nausea and its role in appetite stimulation, read ahead to know more.
Understanding Cannabidiol (CBD)
CBD along with THC are the two major cannabinoids naturally found in the hemp and marijuana plant. They both share the same chemical formula, but different molecular structure resulting in differences in their biological effects on the body, i.e. the former is not psychotropic while the latter is. Because of their similarity, they stimulate appetite due to the influence on the endocannabinoid receptors CB1 and CB2.
Hunger And The Endocannabinoid System
The endocannabinoid system (ECS) is a network of neurotransmitters and chemical messengers spread throughout the body, and this system is responsible for homeostasis. Its two main receptors are CB1 and CB2, the former is found more in the central and peripheral nervous system and the latter is associated with the immune system. From studies it is found that activation of CB1 receptors increases hunger and the ECS has influence on the neurotransmitter dopamine which is released when you eat food.
CBD And Appetite Stimulation
It is clear from research that the effect of CBD in stimulating appetite and reducing nausea or vomiting is due to its effect on the serotonin receptors 5-HT1A. You should also know that the activation of this receptor happens at high cannabidiol concentration and hence the antiemetic effect of CBD oil for nausea.
However, it is also found that cannabidiol suppresses hunger and this is attributed to its allosteric effect on reducing effectiveness of CB1 receptors. This is also the reason why CBD inhibits the adverse effects of THC like paranoia or panic when they are consumed together. Last but not least, its anti-inflammatory effect helps to reduce inflammation in gastrointestinal diseases like irritable bowel syndrome and reduce the severity of its symptoms.
CBD oil for nausea is used by cancer patients undergoing chemotherapy as a complementary medicine to reduce nausea or vomiting and stimulate appetite. Its antiemetic effect is useful in managing symptoms of stomach flu, indigestion and other gastrointestinal issues causing nausea or vomiting.
On a final note, more research is conducted to better understand about the use of CBD in reducing nausea or vomiting and appetite stimulation.